Category: ENT / Laryngology

Nanofat for Injection Laryngoplasty: A Preliminary Study of a New Substrate

Posted in Clinical Trials & Pilot Studies, ENT / Laryngology

Date Published: 11 February 2025 Gidumal et al. evaluate nanofat injection laryngoplasty as a novel treatment for vocal fold atrophy, demonstrating significant improvement in voice function and voice quality with nanofat comparable or superior to microfat, and suggesting nanofat as a promising alternative for vocal atrophy augmentation. The article was published in Journal of Voice.

Adding Nanofat to Fat Grafting to Treat Velar Scarring in Velopharyngeal Incompetence

Posted in Clinical Trials & Pilot Studies, Craniofacial, ENT / Laryngology, Plastic Surgery

Date Published: 23 April 2020 Cantarella et al. evaluate adding nanofat to traditional fat grafting for treatment of velar scarring in velopharyngeal incompetence, reporting that nanofat’s regenerative properties may improve velar scar elasticity and pliability and suggesting it as a promising adjunct to enhance outcomes in mild VPI. The article was published in the Journal […]

Augmentation of Scarred Vocal Folds With Centrifuged and Emulsified Autologous Fat Grafts

Posted in Clinical Trials & Pilot Studies, Craniofacial, ENT / Laryngology, Plastic Surgery

Date Published: 23 June 2020 Salmerón-González et al. evaluate the use of centrifuged and emulsified autologous fat grafts for the treatment of scarred vocal folds and demonstrate improved vocal fold function and mucosal wave characteristics, suggesting this technique as a promising regenerative approach for vocal fold scarring. The article was published in Otolaryngology–Head and Neck […]

Management of Vocal Fold Scars by Concurrent Nanofat and Microfat Grafting

Posted in Clinical Trials & Pilot Studies, ENT / Laryngology

Date Published: 21 November 2018 Cantarella et al. evaluate the use of concurrent nanofat and microfat grafting for the treatment of vocal fold scars, demonstrating improved vocal fold pliability and functional outcomes and suggesting this combined regenerative approach as a promising therapeutic option. The article was published in Journal of Craniofacial Surgery.

Autologous Fat Grafting for the Treatment of Mild to Moderate Velopharyngeal Insufficiency

Posted in Clinical Trials & Pilot Studies, Craniofacial, ENT / Laryngology, Plastic Surgery

Date Published: 31 December 2018 Adams et al. evaluate the effectiveness of autologous fat grafting for treating mild to moderate velopharyngeal insufficiency following cleft palate surgery, demonstrating improved speech outcomes in most patients with no reported complications and suggesting it as a safe, minimally invasive therapeutic option. The article was published in the Journal of […]