Category: Craniofacial

Adding Nanofat to Fat Grafting to Treat Velar Scarring in Velopharyngeal Incompetence

Posted in Clinical Trials & Pilot Studies, Craniofacial, ENT / Laryngology, Plastic Surgery

Date Published: 23 April 2020 Cantarella et al. evaluate adding nanofat to traditional fat grafting for treatment of velar scarring in velopharyngeal incompetence, reporting that nanofat’s regenerative properties may improve velar scar elasticity and pliability and suggesting it as a promising adjunct to enhance outcomes in mild VPI. The article was published in the Journal […]

Augmentation of Scarred Vocal Folds With Centrifuged and Emulsified Autologous Fat Grafts

Posted in Clinical Trials & Pilot Studies, Craniofacial, ENT / Laryngology, Plastic Surgery

Date Published: 23 June 2020 Salmerón-González et al. evaluate the use of centrifuged and emulsified autologous fat grafts for the treatment of scarred vocal folds and demonstrate improved vocal fold function and mucosal wave characteristics, suggesting this technique as a promising regenerative approach for vocal fold scarring. The article was published in Otolaryngology–Head and Neck […]

Autologous Fat Grafting for the Treatment of Mild to Moderate Velopharyngeal Insufficiency

Posted in Clinical Trials & Pilot Studies, Craniofacial, ENT / Laryngology, Plastic Surgery

Date Published: 31 December 2018 Adams et al. evaluate the effectiveness of autologous fat grafting for treating mild to moderate velopharyngeal insufficiency following cleft palate surgery, demonstrating improved speech outcomes in most patients with no reported complications and suggesting it as a safe, minimally invasive therapeutic option. The article was published in the Journal of […]

Can the Autogenous Nanofat Injection Improve the Symptoms of Patients With Temporomandibular Joint Internal Derangement? A Prospective Observational Clinical Study

Posted in Clinical Trials & Pilot Studies, Craniofacial, Ideas & Innovations, Orthopedics, Plastic Surgery, TMJ

Date Published: 13 Nov 2023 Ali et al. evaluate the effectiveness of intra-articular nanofat injection for temporomandibular joint internal derangement, demonstrating improvements in pain, mouth opening, and joint sounds while supporting its potential as a minimally invasive treatment option. The article was published in the The Journal of Craniofacial Surgery.

Assessment of Therapeutic Effect of Intra-Articular Nanofat Injection for Temporomandibular Disorders

Posted in Clinical Trials & Pilot Studies, Craniofacial, Ideas & Innovations, Orthopedics, TMJ

Date Published: May/June 2019 Mahmmood et al. report that intra‑articular nanofat injection in patients with temporomandibular disorders was safe, well‑tolerated, suggesting therapeutic benefit as a minimally invasive treatment option. The article was published in the Journal of Craniofacial Surgery.

Can nano-fat injection in patients with tempromandibular disorder alters salivary matrix metalloproteinases 2 and 9?

Posted in Clinical Trials & Pilot Studies, Craniofacial, Ideas & Innovations, Orthopedics, TMJ

Date Published: 10 January 2024 Jafar & Hadi report that nano‑fat injections in patients with temporomandibular disorder significantly reduce salivary matrix metalloproteinases 2 and 9 levels, suggesting a potential therapeutic effect on extracellular matrix remodeling in TMD. The article was published in the Multidisciplinary Science Journal.