Category: Clinical Trials & Pilot Studies

Ocular Complications Following Autologous Fat Injections into Facial Area: Case Report of a Recovery from Visual Loss After Ophthalmic Artery Occlusion and a Review of the Literature

Posted in Aesthetic Dermatology (Facial Volume Restoration), Clinical Trials & Pilot Studies, Dermatology, Facial Surgery, Facial Volume Restoration, Office Based Aesthetic Medicine, Periorbital Rejuvenation, Plastic Surgery

Date Published: 23 February 2017 Szantyr, et al. present the first report of recovery from vision loss caused by ophthalmic artery occlusion following autologous fat injection. They discuss the importance of awareness of this complication and need for popularizing the treatment method to prevent such consequences. The article was published in the Aesthetic Plastic Surgery Journal.

Autologous lipoaspirate as a new treatment of vulvar lichen sclerosus: A review on literature

Posted in Clinical Trials & Pilot Studies, Gynecology & Female Sexual Wellness, Ideas & Innovations

Date Published: 11 March 2022 Nanouk van der Sluis et al., complete a review of pioneering studies already done to investigate the therapeutic effect of adipose tissue grafting for Lichen Sclerosus. In this review, they provide an overview of these studies and the proposed mechanisms-of-action of using fat grafting to treat LS. The article was published […]

The Influence of Fat Grafting on Skin Quality in Cosmetic Foot Grafting: A Randomized, Cross-Over Clinical Trial

Posted in Clinical Trials & Pilot Studies, Dermatology, Foot & Ankle, Foot Fat Pad, Orthopedics, Skin Rejuvenation, Sports Medicine

Date Published: 10 July 2018 Stephanie E. Farber, et al., conducted a clinical trial with results indicating that pedal fat grafting resulted in a clinically significant and sustained increase in dermal thickness, as well as an improvement in skin quality. The article was published in Aesthetic Surgery Journal.

A New Minimally Invasive Procedure for Treating Plantar Heel Pain – Stromal Vascular Fraction Gel Grafting

Posted in Clinical Trials & Pilot Studies, Foot & Ankle, Foot Fat Pad, Orthopedics, Pain Management, Sports Medicine

Date Published: 5 Nov 2023 Bihua Wu, et al., investigated and found that stromal vascular fraction gel grafting is a safe, effective, and minimally invasive approach to treating plantar heel pain that actually worked to increase the thickness of the heel fat pad. The article was published in Annals of Plastic Surgery.

Autologous Nanofat Injection Combined with Fractional CO2 Laser in the Treatment of Atrophic Acne Scars

Posted in Clinical Trials & Pilot Studies, Combination with Energy Based Devices, Dermatology, Facial Rejuvenation & Skin Quality, Office Based Aesthetic Medicine, Scar Treatment, Skin Scars & Acne Scarring

Date Published: 20 Mar 2024 Mahmoud A Rageh, et al. investigate the role of Nanofat in combination with fractional CO2 laser as a combined approach for treating atrophic acne scarring. The article was published in Clinical, Cosmetic and Investigational Dermatology.

Nanofat Grafting: Basic Research and Clinical Applications

Posted in Clinical Trials & Pilot Studies, Dermatology, Facial Rejuvenation & Skin Quality, Office Based Aesthetic Medicine, Skin Rejuvenation, Techniques & Methods, Techniques & Methods for Fat Harvesting, Processing & Grafting

October 2013 Drs. Tonnard and Verpaele published a study titled “Nanofat Grafting: Basic Research and Clinical Applications” in Plastic and Reconstructive Surgery. The study evaluated the cellular contents of Nanofat and its efficacy in clinical applications which “showed remarkable improvements in skin quality 6 months postoperatively.” Click below to read the full study.

Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study

Posted in Clinical Trials & Pilot Studies, Elbow, Orthopedics

January 2021 Miguel Khoury et al. published “Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study” in The Journal of Experimental Orthopaedics. They studied the “effect of Adipose derived stromal cells (ASCs) injection as therapeutic procedure on the common extensor tendinopathy” and found significant clinical improvement and […]

Safety and Potential Effect of a Single Intracavernous Injection of Autologous Adipose-Derived Regenerative Cells in Patients with Erectile Dysfunction Following Radical Prostatectomy: An Open-Label Phase I Clinical Trial

Posted in Clinical Trials & Pilot Studies, Male Sexual Wellness

March 2016 Martha Kirstine Haahr et al. published “Intracavernous Injection of Autologous Adipose-Derived Regenerative Cells in Patients with Erectile Dysfunction Following Radical Prostatectomy: An Open-Label Phase I Clinical Trial” in EBio Medicine. They completed a human phase 1 trial with autologous adipose-derived regenerative cells (ADRCs) and their results showed that adipose cells are “safe to […]

Application of nanofat for treatment of traumatic faecal incontinence after sphincteroplasty – A pilot study

Posted in Clinical Trials & Pilot Studies, Urology & Colorectal

September 2022 Dr. Katarina Andjelkov et al. published “Application of nanofat for treatment of traumatic feacal incontinence after sphincteroplasty – A pilot study” in Colorectal Disease. They investigated whether nanofat treatment improves continence in women who had previously undergone anal sphincteroplasty with unsatisfactory outcomes and found that “the application of nanofat as an injectable product improves […]

Nanofat Grafting in Facial Rejuvenation: An Innovative Technique

Posted in Clinical Trials & Pilot Studies, Dermatology, Facial Rejuvenation & Skin Quality, Office Based Aesthetic Medicine, Skin Rejuvenation

Sophie Menkes conducted this study into using nanofat in facial rejuvenation. She aimed to assess whether the novel nanofat grafting procedure improves skin quality while yielding a regenerative effect and whether this novel technique can also achieve a lifting effect. Click here to read and access this article.

Evaluation of Adipose Cell-Based Therapies for the Treatment of Thumb CMCJ Osteoarthritis

Posted in Clinical Trials & Pilot Studies, Hand & Wrist, Orthopedics

Eleni Karagergou et al. reviewed the current published research studying the use of enzymatic or mechanically processed adipose tissue in treating thumb carpometacarpal joint osteoarthritis. In their study, they state, “Although the number of available studies is limited, the results of intra-articular injection of autologous fat in thumb CMCJ osteoarthritis are positive and very promising.” […]

One-Year Outcomes of Intraarticular Fat Transplantation for Thumb CMCJ Osteoarthritis

Posted in Clinical Trials & Pilot Studies, Hand & Wrist, Orthopedics

Elisabeth Haas, MD et al. conducted a study using autologous fat transfer as a treatment for patients with thumb carpometacarpal joint osteoarthritis who hoped to postpone the need for surgery. Her study found that “autologous fat grafting is a safe procedure and provided appreciable benefit in 61 percent of studied cases 12 months postoperatively.” Access […]