Category: Orthopedics

Can the Autogenous Nanofat Injection Improve the Symptoms of Patients With Temporomandibular Joint Internal Derangement? A Prospective Observational Clinical Study

Posted in Clinical Trials & Pilot Studies, Craniofacial, Ideas & Innovations, Orthopedics, Plastic Surgery, TMJ

Date Published: 13 Nov 2023 Ali et al. evaluate the effectiveness of intra-articular nanofat injection for temporomandibular joint internal derangement, demonstrating improvements in pain, mouth opening, and joint sounds while supporting its potential as a minimally invasive treatment option. The article was published in the The Journal of Craniofacial Surgery.

Assessment of Therapeutic Effect of Intra-Articular Nanofat Injection for Temporomandibular Disorders

Posted in Clinical Trials & Pilot Studies, Craniofacial, Ideas & Innovations, Orthopedics, TMJ

Date Published: May/June 2019 Mahmmood et al. report that intra‑articular nanofat injection in patients with temporomandibular disorders was safe, well‑tolerated, suggesting therapeutic benefit as a minimally invasive treatment option. The article was published in the Journal of Craniofacial Surgery.

Can nano-fat injection in patients with tempromandibular disorder alters salivary matrix metalloproteinases 2 and 9?

Posted in Clinical Trials & Pilot Studies, Craniofacial, Ideas & Innovations, Orthopedics, TMJ

Date Published: 10 January 2024 Jafar & Hadi report that nano‑fat injections in patients with temporomandibular disorder significantly reduce salivary matrix metalloproteinases 2 and 9 levels, suggesting a potential therapeutic effect on extracellular matrix remodeling in TMD. The article was published in the Multidisciplinary Science Journal.

Intra-Articular Injection of Adipose-Derived Stromal Vascular Fraction in Osteoarthritic Temporomandibular Joints: Study Design of a Randomized Controlled Clinical Trial

Posted in Clinical Trials & Pilot Studies, General Orthopedics, Ideas & Innovations, Orthopedics, TMJ

Date Published: 10 February 2024 Schipper et al. investigate intra-articular injection of adipose-derived stromal vascular fraction for osteoarthritic temporomandibular joints, aiming to evaluate its safety and efficacy as a regenerative treatment approach. The article was published in Bioengineering.

Arthroscopy With Adipose-Derived Stromal Vascular Fraction Using a Selective Tissue Engineering Photo-Stimulation Technique for the Treatment of Mild to Moderate Knee Osteoarthritis

Posted in General Orthopedics, Knee, Orthopedics, Pain Management, Techniques & Methods for Fat Harvesting, Processing & Grafting

Date Published: 4 May 2024 José Paulo Gabbi Aramburu Filho et al., provide a step-by-step guide of arthroscopic treatment of mild to moderate knee osteoarthritis with photo-stimulated SVF via a “One S.T.E.P.” technique. The article was published in: Arthroscopy Techniques.

The Influence of Fat Grafting on Skin Quality in Cosmetic Foot Grafting: A Randomized, Cross-Over Clinical Trial

Posted in Clinical Trials & Pilot Studies, Dermatology, Foot & Ankle, Foot Fat Pad, Orthopedics, Skin Rejuvenation, Sports Medicine

Date Published: 10 July 2018 Stephanie E. Farber, et al., conducted a clinical trial with results indicating that pedal fat grafting resulted in a clinically significant and sustained increase in dermal thickness, as well as an improvement in skin quality. The article was published in Aesthetic Surgery Journal.

A New Minimally Invasive Procedure for Treating Plantar Heel Pain – Stromal Vascular Fraction Gel Grafting

Posted in Clinical Trials & Pilot Studies, Foot & Ankle, Foot Fat Pad, Orthopedics, Pain Management, Sports Medicine

Date Published: 5 Nov 2023 Bihua Wu, et al., investigated and found that stromal vascular fraction gel grafting is a safe, effective, and minimally invasive approach to treating plantar heel pain that actually worked to increase the thickness of the heel fat pad. The article was published in Annals of Plastic Surgery.

Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study

Posted in Clinical Trials & Pilot Studies, Elbow, Orthopedics

January 2021 Miguel Khoury et al. published “Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study” in The Journal of Experimental Orthopaedics. They studied the “effect of Adipose derived stromal cells (ASCs) injection as therapeutic procedure on the common extensor tendinopathy” and found significant clinical improvement and […]

Autologous Adipose-Derived Tissue Stromal Vascular Fraction (AD-tSVF) for Knee Osteoarthritis

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Knee, Orthopedics

Ibrahim Vargel, et. al. conducted this review of techniques involving autologous adipose-derived tissue stromal vascular fraction (AD-tSVF) for knee osteoarthritis in 2022. Click below to access the full study.

Evaluation of Adipose Cell-Based Therapies for the Treatment of Thumb CMCJ Osteoarthritis

Posted in Clinical Trials & Pilot Studies, Hand & Wrist, Orthopedics

Eleni Karagergou et al. reviewed the current published research studying the use of enzymatic or mechanically processed adipose tissue in treating thumb carpometacarpal joint osteoarthritis. In their study, they state, “Although the number of available studies is limited, the results of intra-articular injection of autologous fat in thumb CMCJ osteoarthritis are positive and very promising.” […]

One-Year Outcomes of Intraarticular Fat Transplantation for Thumb CMCJ Osteoarthritis

Posted in Clinical Trials & Pilot Studies, Hand & Wrist, Orthopedics

Elisabeth Haas, MD et al. conducted a study using autologous fat transfer as a treatment for patients with thumb carpometacarpal joint osteoarthritis who hoped to postpone the need for surgery. Her study found that “autologous fat grafting is a safe procedure and provided appreciable benefit in 61 percent of studied cases 12 months postoperatively.” Access […]

Advances of Stem Cell Based Therapeutic Approaches for Tendon Repair

Posted in Achilles Tendinopathy, General Orthopedics, Orthopedics, Sports Medicine

April 29th, 2019 Authors Lidi Liu, et al, review recent progress on the use of stem cell therapy for tendon repair. This study was published in the Journal of Orthopaedic Translation. READ THE STUDY NOW Want to learn more about tendon repair? Visit the SDARTs Online Learning Center >