Category: Ideas & Innovations

Fat embolism syndrome: a review in cosmetic surgery

Posted in Facial Surgery, Facial Volume Restoration, Ideas & Innovations, Latest News, Office Based Aesthetic Medicine, Plastic Surgery, Techniques & Methods for Fat Harvesting, Processing & Grafting

Date Published: 30 August 2024 Kim, et al. investigate fat embolism syndrome, an associated side effect of liposuction and fat grafting procedures, and identify effective treatment options based on the subtypes of this condition. The article was published in the Kosin Medical Journal.

The Regenerative Marriage Between High-Density Platelet-Rich Plasma and Adipose Tissue

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Ideas & Innovations, Latest News, PRP & Adipose, Regenerative Potential & Mechanisms of Nanofat, Wound Healing

Date Published: 27 February 2025 Everts et al., investigate the synergistic effects of combining HD-PRP with adipose tissue, particularly looking at the role of t-SVF in these effects. They find that the combination multicellular approach using both of these cellular biological products leads to improved tissue repair, regeneration and, wound healing. The article was published […]

Autologous lipoaspirate as a new treatment of vulvar lichen sclerosus: A review on literature

Posted in Clinical Trials & Pilot Studies, Gynecology & Female Sexual Wellness, Ideas & Innovations

Date Published: 11 March 2022 Nanouk van der Sluis et al., complete a review of pioneering studies already done to investigate the therapeutic effect of adipose tissue grafting for Lichen Sclerosus. In this review, they provide an overview of these studies and the proposed mechanisms-of-action of using fat grafting to treat LS. The article was published […]

Discussion: Protein profiling of mechanically processed lipoaspirates: Discovering wound healing and antifibrotic biomarkers in nanofat

Posted in Basic Science & Research, Ideas & Innovations, Regenerative Potential & Mechanisms of Nanofat

November 2021 Dr. Ramon Llull wrote this discussion titled “Discussion: Protein profiling of mechanically processed lipoaspirates: Discovering wound healing and antifibrotic biomarkers in nanofat” in Plastic and Reconstructive Surgery. Click below to read the full article.

Impact of Aging on the Regenerative Properties of Bone Marrow, Muscle & Adipose-Derived Mesenchymal

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Ideas & Innovations

January 22nd, 2019 Olivia S. Beane, Vera C. Fonseca, Leroy L. Cooper, Gideon Koren, and Eric M. Darling look at the effects of aging on the regenerative properties of bone marrow-, muscle-, and adipose-derived mesenchymal stem/ stromal cells. The article was published in PLOS ONE. Want to learn more about this topic? Visit the SDARTs […]

Overview of COVID-19 Lung Damage Clinical Trial

Posted in Clinical Trials & Pilot Studies, Ideas & Innovations

June 16th, 2020 SDARTs faculty member, Robert W. Alexander, MD, DDS, is the Principle Investigator on a first-in-human clinical trial to treat post-COVID 19 survivors with AD cSVF. Many moderate to severe post-COVID 19 survivors experience compromised lung function. As a proposed solution, adipose-derived cellular stromal vascular fraction (AD cSVF) may be effective in reversing […]

Human Stromal Cell Aggregates Concentrate Adipose Tissue Constitutive Cell Population

Posted in AD-cSVF, AD-tSVF, AD-MSC, Adipose Tissue Complex, Basic Science & Research, Ideas & Innovations

January 28th, 2021 SDARTs faculty member, Ramon Lull, MD, PhD, et al, published a new study on “Human Stromal Cell Aggregates Concentrate Adipose Tissue Constitutive Cell Population by In Vitro DNA Quantification Analysis.” This study was published in the Plastic & Reconstructive Surgery Journal. Want to learn more from Dr. Ramon Llull? Visit the SDARTs […]

Comparison of Harvest and Processing Techniques for Fat Grafting and Adipose Stem Cell Isolation

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Ideas & Innovations, Techniques & Methods for Fat Harvesting, Processing & Grafting

March 14th, 2019 Study authors Christine Fisher, M.D., Tara L. Grahovac, M.D., Mark E. Schafer, Ph.D., Ron D. Shippert, M.D., Kacey G. Marra, Ph.D., and SDARTs faculty member J. Peter Rubin, M.D. compared techniques for processing and harvesting adipose tissue to determine effects on fat grafting outcomes. This study was published in the Plastic and […]

Potential Use of Cellular Stromal Vascular Fraction in Post-COVID-19 Injury and Respiratory Distress

Posted in Clinical Trials & Pilot Studies, Ideas & Innovations

June 2nd, 2020 SDARTs faculty member, Robert W. Alexander, MD, DDS, is the Principle Investigator on a first-in-human clinical trial to treat post-COVID 19 survivors with AD cSVF. Many moderate to severe post-COVID 19 survivors experience compromised lung function. As a proposed solution, adipose-derived cellular stromal vascular fraction (AD cSVF) may be effective in reversing […]

Nanofat Cell Aggregates: A Stromal Cell Inoculum For Regenerative Site-Specific Therapies

Posted in AD-cSVF, AD-tSVF, AD-MSC, Adipose Tissue Complex, Basic Science & Research, Ideas & Innovations

October 23rd, 2019 Authors Borja Sesé (Ph.D.), SDARTs Faculty member, Ramon Llull (M.D., Ph.D.), et al, conducted a study on the cell yields of mechanically disaggregated fat tissue (Tulip True NanoFat) vs. enzymatic digestion. This study was published in the Plastic and Reconstructive Surgery Journal. Want to learn more about nanofat? Visit the SDARTs Online […]

Platelet-Rich Plasma and Platelet-Rich Fibrin Enhance the Outcomes of Fat Grafting

Posted in Ideas & Innovations, PRP & Adipose

October 23rd, 2019 Authors Shaoheng Xiong, M.D., et al, conducted a study on the effects of platelet-rich plasma and platelet-rich fibrin on the long-term tissue absorption of grafted fat. This article was published in the Plastic and Reconstructive Surgery Journal. Want to learn more about PRP and PRF? Visit the SDARTs Online Learning Center >

Nanofat Needling: A Novel Method for Uniform Delivery of Adipose-Derived Stromal Vascular Fraction

Posted in Facial Surgery, Ideas & Innovations, Nanofat Microneedling, Office Based Aesthetic Medicine, Plastic Surgery

May 13th, 2019 SDARTs faculty members Alexis Verpaele, M.D., Ph.D., and Patrick Tonnard, M.D., Ph.D., along with Charan Jeganathan, M.D., and Lisa Ramaut, M.D., authored this study on the use of a new technique, called nanofat needling, for delivering AD-SVF to the skin. This study was published in Plastic and Reconstructive Surgery. READ THE STUDY […]